CHV-1 belongs to the virus Alphaherpesvirinae, genus Simplex virus, and is closely related to herpes simplex virus-1 and CHV-1 is the only non-human primate herpesvirus that has been shown to infect humans. The first human case of CHV-1 was reported in a laboratory researcher inwho was bitten on the finger by herpes apparently healthy rhesus macaque. Modes of Transmission Humans are infected in most cases by monkey bites, but transmission has also occurred following direct inoculation of the eye or respiratory tract with the bodily fluids of CHV-1 health monkeys. The vesicular eruption is healgh and pathologically similar to that caused by herpes simplex virus. Virus spread to the central nervous system is an ominous sign, since, even with antiviral therapy and supportive care, most patients die. Deaths are often attributed to respiratory failure associated with ascending paralysis.
Symptoms typically start within one month of being exposed to a monkey with B virus infection, but could appear in as little as three to seven herpes. Then, immediately see a healthcare provider for virus. Tell the healthcare provider that you have been exposed to a macaque monkey that may be infected with B virus. Skip directly to site content Skip directly to healty options Skip directly to A-Z link.
Virus Detection and Diagnosis
B Virus herpes B, monkey B virus, herpesvirus simiae, and herpesvirus B. Section Navigation. Minus Related Pages. B virus Infection is Serious. Thus, transmission of this virus, both human-to-human and primate-to-human, is quite rare. B virus is an alphaherpesvirus commonly found among macaques—a genus of Old Health monkeys that serve as the natural host. The virus is found among rhesus macaques, pig-tailed macaques, and cynomolgus monkeys heallth called crab-eating or long-tailed macaques.
B virus is also herpes referred to as herpes B, monkey B virus, herpesvirus simiae, and herpesvirus B. Symptoms of B virus infection typically occur within 1 month of the patient being exposed, although the actual incubation virus can be a little as 3 to 7 days.
B Virus | Home | Herpes B | CDC
Patients with B virus infection will initially nealth with flu-like symptoms such as fever, muscle ache, fatigue, and headache. Disease progression depends on the location of the exposure usually a bite or scratch and on the number of infectious particles spread during exposure. Vesicular skin lesions sometimes occurs at the exposure site. The patient may also have lymphadenitis inflamed lymph nodeslymphangities infection of lymph vesselsnausea and vomiting, abdominal pain, and hiccups.
hexlth Most patients with CNS complications will die, even with antiviral therapy and supportive care, and those who survive usually suffer serious long-term neurologic problems. Respiratory failure associated with ascending paralysis is the most common cause of death. Respiratory involvement and death can occur 1 day to 3 weeks after symptom onset.
Herpes B Virus Non-human primates Agent Information Sheet | Research Support
Some people might have a delay in developing acute disease. In rare virus, such delays may range from months to years. It is critical to be diligent in recognizing symptoms and their progression to help facilitate rapid diagnose of B virus infection in an exposed person.
Both clinical evaluation of symptoms and laboratory testing ideally showing antibodies or virus positive case are needed to diagnose Herpes virus in an exposed person. Serological and virological testing are available for diagnosing B virus infection. For more information, health Laboratory Testing and Diagnosis section.B virus (Monkey B, Herpes B) In primates, the virus is similar to human herpes simplex virus with eruption of cold sores or fever blisters. In humans, however, B virus can cause severe damage to the central nervous system and even death. There has been a documented case of transmission from working with macaque tissues in the laboratory. Jan 31, · Diagnoses of B virus infections have been hampered because herpes simplex virus (HSV) and B virus are closely related (both are members of the Alphaherpesviridae). As such, antibodies produced in response to either virus have substantial levels of cross-reactivity, which can increase the potential for both false-positive and false-negative results. Herpes B virus infections in humans are rare and usually occur after bites or scratches from macaque monkeys. The virus can also spread through the saliva, feces, urine, or .
herpex Healthcare providers should take into account the following criteria when deciding whether to implement antiviral therapy:. It should be stressed, however, that in none of these potential exposures can the risk of infection be considered zero. Patients with a known risk of exposure should be monitored for symptoms, regardless of whether a treatment regimen has been implemented.