Shingles is a viral infection that causes a painful rash. Although shingles can occur anywhere on your body, it most often appears as a single stripe of blisters that wraps around either the left or the right side of your torso. Shingles is caused by the varicella-zoster virus — the same virus that causes chickenpox. After you've had chickenpox, the virus lies inactive in nerve tissue near your spinal cord and brain. Years later, the virus may reactivate as shingles. While it isn't a life-threatening condition, shingles can be very painful.
An estimated 1 million people get shingles each year in this country. Even children can get shingles.
Your risk of shingles increases as you get older. Shingles is caused by varicella zoster virus VZVthe same virus that causes chickenpox. After a person recovers from chickenpox, the virus stays dormant inactive in the body. This virus can reactivate years later, causing shingles.
Two shingles vaccines are licensed in the United States, and recommended to prevent shingles. Zoster vaccine live ZVL, Zostavax has been in use since Recombinant zoster vaccine RZV, Shingrixhas been in use sinceand is recommended as the preferred shingles vaccine.
Skip directly to site content Skip directly to page options Skip directly to A-Z link. Multiple studies and surveillance data, at least when viewed superficially, demonstrate no consistent trends in incidence in the U. Shingles has a long recorded history, although historical accounts fail to distinguish the blistering caused by VZV and those caused by smallpox ergotismand erysipelas.
In the late 18th century William Heberden established a way to differentiate between the and smallpox,  and in the late 19th century shingles was differentiated from erysipelas. The first indications that chickenpox and shingles were caused by the same virus were noticed at the beginning of the 20th century. Physicians began to report that cases of shingles were often followed by chickenpox in the younger people who lived with the person with shingles.
The idea of an association between the two diseases gained strength when it was same that lymph from a person with shingles could induce zoster in young volunteers.
This was herpes proved by the first isolation of the virus in cell culturesby the Nobel laureate Thomas Huckle Wellerin Until the s the disease was considered benign, and serious complications were thought to be very rare. Further studies during the s on immunosuppressed individuals showed that right disease was not as shingles as once thought, and the search for various therapeutic and preventive measures began.
In historical shingles studies, shingles incidence generally increased with age. However, in his paper, Hope-Simpson suggested that the "peculiar age distribution of zoster may in part reflect the frequency with which the different age groups encounter cases of varicella and because of zowter ensuing boost to their antibody protection have their attacks of zoster postponed".
The family name of all the herpesviridae derives from the Greek shinyles herpein "to creep" referring to the latent, recurring infections typical of this group of viruses.
In Arabic its name means "belt of fire", while in Spanish it means "small snake"; in Hindi it means "big rash"  and in Norwegian its name is helvetesildliterally "hell's fire". Until the mid s, infectious complications of the central nervous system CNS caused by VZV reactivation were regarded as rare. The presence of rash, as well as specific neurological symptoms, were required to diagnose a CNS infection caused by VZV.
SincePCR testing has become more widely used, and the number of diagnosed cases of CNS infection has increased.
Shingles (Herpes Zoster): Symptoms, Causes, Contagiousness, Vaccine, Diagnosis, and Treatment
Classic textbook descriptions state that VZV reactivation in the CNS is restricted to immunocompromised individuals and the elderly; however, recent studies have found that most patients are immunocompetent, and less than 60 years old. The frequency of CNS infections presented at the emergency room of a community hospital is not negligible, so a means of diagnosing cases is needed. Negative PCR does not rule out VZV involvement, but a positive PCR can be used for diagnosis, and appropriate treatment started for example, antivirals can be prescribed rather than antibiotics.
The introduction of DNA analysis techniques has shown some complications of varicella-zoster to be more common than previously thought. For example, sporadic meningoencephalitis ME caused by varicella-zoster was regarded as rare disease, mostly related to childhood chickenpox. However, meningoencephalitis caused by varicella-zoster is increasingly recognized as a predominant cause of ME among immunocompetent adults in non-epidemic circumstances.
Diagnosis of complications of varicella-zoster, particularly in cases where the disease reactivates after years or decades of latency, are difficult.Sep 12, · People tend to wonder whether shingles and herpes are the same. The answer would be, not quite! Shingles and herpes are related and if you really want to stretch the definition, then you can say that shingles is a form of herpes in terms that they are both caused by viruses in the HHV family, and that both shingles and herpes are contagious,    however, the similarity ends there. Shingles, also known as zoster or herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area. Typically the rash occurs in a single, wide stripe either on the left or right side of the body or face. Two to four days before the rash occurs there may be Causes: Varicella zoster virus (VZV). Shingles is also known as herpes zoster because it is caused by the varicella-zoster virus. This virus is part of a group of viruses called herpes viruses, which also includes the viruses that cause oral and genital herpes. Herpes zoster is the same virus that causes chickenpox.
A rash shingles can be present or absent. Symptoms vary, and there is significant overlap in symptoms with herpes-simplex symptoms.
Although DNA analysis techniques such as polymerase chain reaction PCR can be used to look for DNA of herpesviruses in spinal fluid or blood, the results same be negative, even in cases where other definitive symptoms exist. For example, in the past, clinicians believed that encephalitis was caused by herpes shinglesand that patients always died or developed serious long right function problems.
People were diagnosed at autopsy or by brain biopsy. Brain biopsy is not undertaken lightly: it is reserved only for serious herpes that cannot zoster diagnosed by less invasive methods. For this reason, knowledge of these herpes virus conditions was limited to severe cases. DNA techniques have made it possible to diagnose "mild" cases, caused by VZV or HSV, in which the symptoms include fever, headache, and altered mental status.
Mortality rates in treated patients are decreasing. From Wikipedia, the free the. Redirected from Herpes zoster.
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Shingles - Wikipedia
London: Elsevier Health Sciences. FDA Consumer. Archived from the original on Retrieved Revised June Proceedings of the Royal Society of Medicine.Shingles, also known as zoster or herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area. Typically the rash occurs in a single, wide stripe either on the left or right side of the body or face. Two to four days before the rash occurs there may be Causes: Varicella zoster virus (VZV). Shingles is also known as herpes zoster because it is caused by the varicella-zoster virus. This virus is part of a group of viruses called herpes viruses, which also includes the viruses that cause oral and genital herpes. Herpes zoster is the same virus that causes chickenpox. That’s when it lands its second punch: shingles, also called herpes zoster. Shingles Risk Factors. A weakened immune system might wake up the virus. After you’ve had chickenpox, you’re more.
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Shingles | Home | Herpes Zoster | CDC
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Shingles - Symptoms and causes - Mayo Clinic
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